integrative database for protein Cysteine Modifications in eukaryotes
Result
Related information of protein
OrganismHomo sapiens
UniProt IDQ9NYG8
Gene nameKCNK4
Protein namePotassium channel subfamily K member 4
FunctionVoltage-insensitive potassium channel1. Channel opening is triggered by mechanical forces that deform the membrane4. Channel opening is triggered by raising the intracellular pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity).
SequenceMRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPRQDSPAYQPLVWFWILLGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRAGPAAPPPEKEQPLLPPPPCPAQPLGRPRSPSPPEKAQPPSPPTASALDYPSENLAFIDESSDTQSERGCPLPRAPRGRRRPNPPRKPVRPRGPGRPRDKGVPV

Cysteine modification and structural characteristics

Detailed information on cysteine modification
Uniprot ID Gene name Position Sequence window Modification Source
Q9NYG8 KCNK4 52 KFLRAHPCVSDQELG Disulfide bond (-SSR) UniProt